Results The peroxide bridge is the active center of QHS and induced by ferrous iron to produce cyclic product. 结果过氧桥键是青蒿素类化合物的活性中心,在Fe2+影响下过氧键逐渐裂解,两个氧原子与Fe2+以共价键结合形成环状加成产物。
A quantum chemistry investigation on antimalarial mechanism of Qinghaosu based on cleavage of the peroxide bridge 基于过氧键裂解的青蒿素抗疟机制量子化学研究
The fluorescence resulted is related to the existence of the peroxide bridge moiety of t. 荧光的产生与过氧基的存在有关。
Dihydroartemisinin ( DHA) is a strongly active artemisinin-based medicine in the all derivatives, which is returns to original state by artemisinin after four hydrogen boron sodium becomes, has the unique peroxide bridge structure. 双氢青蒿素(DHA)是一种青蒿素类药物中活性较强的衍生物,是由青蒿素经四氢硼钠还原而成[1],具有独特的过氧桥结构。
In addition, it is considered that ROS result in cell death by activation of intracellular peroxide bridge. 另外,有学者研究认为,细胞内过氧化桥的激活是细胞内过氧化物导致的细胞死亡的原因。